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KMID : 1103920130190010082
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Korean Journal of Hepatology
2013 Volume.19 No. 1 p.82 ~ p.86
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Two cases of telbivudine-induced myopathy in siblings with chronic hepatitis B
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Kim Eun-Hye
Park Ha-Na
Lee Kun-Ho
Ahn Sang-Hoon
Kim Seung-Min
Han Kwang-Hyub
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Abstract
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Telbivudine is an L-nucleoside analogue with potent antiviral activity against hepatitis B virus (HBV). Clinical trials have shown that telbivudine has a more potent and sustained antiviral activity with a lower frequency of viral resistance than lamivudine. Although there are several reports concerning the safety profile of telbivudine, most adverse events are described as mild and transient in nature. Here we report two cases of telbivudine-induced myopathy in patients with chronic hepatitis B who were siblings.
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KEYWORD
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Telbivudine, Hepatitis B, Adverse effects, Myopathy
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